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Holmium laser enucleation of the prostate (HoLEP) is a treatment for an enlarged prostate (benign prostatic hyperplasia).
During HoLEP, a laser is used to precisely remove the obstructive portion of the prostate, similar to open surgery without the need for incisions. A separate instrument called a morcellator is then used to cut the prostate tissue into easily removable fragments. With HoLEP, surgeons remove the entire portion of the prostate gland that can block urine flow, which improves urinary symptoms and provides a lasting solution as there is nothing to grow back following this procedure.
HoLEP is an effective and less invasive alternative to older, more traditional methods of removing prostate obstructions. In addition, HoLEP preserves removed tissue for microscopic examination. After the procedure, Mayo Clinic pathologists can examine the tissue for the presence of other conditions, including prostate cancer.
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